Garcinia cambogia -a tropical fruit that belongs to the mangosteen family- is one of the common ingredients in commercial weight loss product. The active constituent in garcinia, hydroxycitric acid reduces the body weight and insulin output based on the animal studies.
Thus it represents the possible application for the treatment of obesity and diabetes. But for best result, consult to the doctor is the best solution before taking the garcinia.
Drugs.com, which provides the peer-reviewed medical information to the publics, shows that garcinia can reduce the lipid levels, LDL cholesterol, adipose tissue and body weight in animal studies. The garcinia extracts also increases the fats oxidation and raises the healthy HDL cholesterol. In several clinical trials and studies, garcinia extracts lowered the LDL cholesterol and triglycerides and caused the weight loss in human
Garcinia’s inhibition of synthesis of lipids causes glycogen to increase in the liver; the resulting satiety signals sent to the brain that will cause reduced appetite. Garcinia also may have beneficial effects on gastric ulcers.
In a 12-week-length clinical study published in 2000 in the “Journal of International Medical Research,” 300 mg of garcinia extract a day, along with other herbs, was given to obese volunteers. The group receiving garcinia got a significant difference in weight loss over the control group — 3.5 kg versus 1.2 kg — with 85 percent of the reduction due to fat loss. More extensive study was called for to determine effective doses. In an animal study published in 2011 in “Lipids in Health and Disease,” garcinia helped to alleviate the damaging effects of high-fat and high-sugar diets fed to rats. In addition to ameliorating negative effects, garcinia also functioned as an antioxidant, decreasing oxidative stress in renal tissues.
A typical dose of garcinia is 300 to 500 mg taken three times a day with water half an hour before meals. Drugs.com lists 1,500 mg a day as the maximum dose. Adverse reactions to garcinia are usually mild and include dizziness, dry mouth, headache, nausea and diarrhea. Garcinia can interact with prescription medications. Consult your doctor before taking garcinia. Don’t take garcinia if you are pregnant, breastfeeding or have diabetes.